Rev. Saúde Pública 2021;55: 15

Neurodevelopment in the third year of life in children with antenatal ZIKV-exposure

Carolina Yuri Panvequio , Deyse Mayara Rodrigues , Carolina Barbosa de , Paula Fernanda Augusto , Luana , Christa , Peter B. , Patrícia , Ana Carolina Basso , Karin , Renata Hydee

DOI: 10.11606/s1518-8787.2021055002798

ABSTRACT

We report cognitive, language and motor neurodevelopment, assessed by the Bayley-III test, in 31 non-microcephalic children at age 3 with PCR-confirmed maternal Zika virus exposure (Rio de Janeiro, 2015–2016). Most children had average neurodevelopmental scores, however, 8 children (26%) presented delay in some domain. Language was the most affected: 7 children (22.6%) had a delay in this domain (2 presenting severe delay). Moderate delay was detected in the cognitive (3.2%) and motor (10%) domains. Maternal illness in the third trimester of pregnancy and later gestational age at birth were associated with higher Bayley-III scores. Zika-exposed children require long-term follow-up until school age.

Neurodevelopment in the third year of life in children with antenatal ZIKV-exposure

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